I think it says something about the region, about what is important there. A lot are neutral, but some are ridiculous -- liposuction, jesus saves, abortion will take you to hell, matress discounters, private investigator services for when your loved one is cheating on you, snake petting zoo next exit. One can argue, yeah it is free market, if you own the land next to the freeway, you can do whatever. But another argument is it make the whole area look bad.