> We have two broad options for reducing the number of dangerous COVID mutations
This is a false dichotomy, we have way more than two options. Below you'll find that I have supported my claim with exceptionally well cited publications and results from recent high quality clinical trials showing promising results.
A) strategies to prevent SARS-CoV-2 transmission that exert specific pressure on other proteins (e.g., antiviral prophylactics) [1][2][3][4][5][6]
B) strategies that do not exert a specific selective pressure on the virus (e.g., high-efficiency air filtration, masking, ultraviolet air purification)
C) Vaccines are absolutely part of the answer here. However, compulsory mass vaccination alone is exceedingly unlikely to be a solution - for all the reasons and evidence put forth in the citations of my previous comment - and because data from all over the world is showing that high vaccination rates alone are not preventing the dominance of VOCs [7][8].
This is a false dichotomy, we have way more than two options. Below you'll find that I have supported my claim with exceptionally well cited publications and results from recent high quality clinical trials showing promising results.
A) strategies to prevent SARS-CoV-2 transmission that exert specific pressure on other proteins (e.g., antiviral prophylactics) [1][2][3][4][5][6]
B) strategies that do not exert a specific selective pressure on the virus (e.g., high-efficiency air filtration, masking, ultraviolet air purification)
C) Vaccines are absolutely part of the answer here. However, compulsory mass vaccination alone is exceedingly unlikely to be a solution - for all the reasons and evidence put forth in the citations of my previous comment - and because data from all over the world is showing that high vaccination rates alone are not preventing the dominance of VOCs [7][8].
[1] Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19) https://scholarlycommons.henryford.com/cgi/viewcontent.cgi?a...
[2] Multidrug treatment for COVID-19 https://www.jstage.jst.go.jp/article/ddt/advpub/0/advpub_202...
[3] Ivermectin in combination with doxycycline for treating COVID-19 symptoms: a randomized trial https://pubmed.ncbi.nlm.nih.gov/33983065/
[4] Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19 https://pubmed.ncbi.nlm.nih.gov/33306283/
[5] A review of therapeutic agents and Chinese herbal medicines against SARS-COV-2 (COVID-19) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237953/
[6] Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19 https://www.frontiersin.org/articles/10.3389/fphar.2021.6526...
[7] Update on Emerging SARS-CoV-2 Variants and COVID-19 vaccines https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-...
[8] COVID-19 Science Update released: August 13, 2021 Edition 102 https://www.cdc.gov/library/covid19/08132021_covidupdate.htm...