There is something incomplete feeling about just the default styling. If you're going for a brutalist design mentality then sure, go for it, but sometimes the appearance actually does matter
I'm not against using font style; I'm against (or more like, failed to see the point) to manually craft a complex "system font stack" to achieve.. basically the same thing as sans-serif but worse.
If you're building a web app (say, via electron) as opposed to a site or document, using the system font stack will make that app fit into the desktop environment much better than Arial, Times New Roman and Courier New will.
What is being compared? Because to me it read like a question of choosing 'sans-serif' over 'ui-system-font-sans' or whatever in your CSS. Nothing more than that.
"System font stack" — which I took to mean the longish list of commonly known default fonts for a bunch of OSes brought up earlier in the thread — with a CSS value of "sans-serif".
There was no mention of direct use of Arial, Times New Roman or Courier that I could see, so I don't see why bring it up.