In the '00s and early '10s there was a London startup, Resolver Systems [1] , that was trying to bring Python and spreadsheets together. Alas they didn't make it but I wonder if that was because Python had a much smaller mindshare back then.
Anaconda is also a heavy sponsor of PyScript. The https://pyscript.com website is an online IDE for quickly trying out PyScript and building a website. If you like PythonAnywhere, you will love pyscript.com as well.
[1] http://www.resolversystems.com