The biggest drawback is no Thunderbolt. The biggest sell for Macs right now is the ability to daisy chain them with the new RDMA update. A used M1 Mac Mini is more valuable than this.
Listen I bought six Retina displays, I don't also have money for a new Mac. Of course I'm going to complain about the lack of Thunderbolt daisy chaining after my frivolous expenses come home to roost.
The Neo is basically the mac flavor of an iPad meant for schoolchildren. It's a Chromebook competitor, not meant for whatever kooky AI shit you're doing at home.