> But as laboratory scientists know, getting mice or other animals hooked on nicotine all by its lonesome is dauntingly difficult. As a 2007 paper in the journal Neuropharmacology put it, “Tobacco use has one of the highest rates of addiction of any abused drug. Paradoxically, in animal models, nicotine appears to be a weak reinforcer.”
Uh, that sounds wrong.
"Snus" users get addicted. That is tobacco, even if it isn't burned. But afaik, users of e-cigarettes also get dependent -- that isn't tobacco.